Treatment with testosterone could help tackle depression in men, according to a review of studies which found supplements of the hormone appear to improve mood.
About 100 million men around the world are thought to have depressive disorders, and almost 17% of men in the UK are thought to have symptoms of depression or anxiety.
However, evidence has been mixed on whether there is a link between testosterone levels and depression, and whether testosterone treatment could help with mood disorders in at least some cases. At present it is not recommended as a treatment for depression by the UK health watchdog, Nice.
We wanted really to clear up the picture and try to find out what is really going on, and is testosterone something that might be one day interesting for clinicians for treatment of depressive disorders or not, said Prof Andreas Walther, a co-author of the research, from the German university TU Dresden.
Writing in the journal Jama Psychiatry, Walther and ...