October 12, 2018
Older patients benefit from treatment of superficial bladder cancer even if they have multiple chronic conditions, a new study suggests.
Treatment of superficial bladder cancer improves survival among older patients despite multiple chronic conditions (MCC), new study findings suggest.
Currently, older adults with superficial bladder cancer may be subject to over- or undertreatment because it is hard to sort out who will benefit from transurethral resection or intravesical therapy due to concerns about competing chronic conditions, lead investigator Tullika Garg, MD, MPH, of Geisinger Medical Center in Danville, Pennsylvania, told Renal & Urology News. In our study, we found that older, medically complex patients with superficial bladder cancer derive an overall survival benefit from treatment, even within the context of multiple chronic conditions.However, this benefit was tempered by the strong association between multiple chronic conditions and death.
Dr Garg and his collaborators studied 1800 patients aged 60 years or older, of whom 66.9% had MCC (2 or more chronic conditions at baseline). Patients who underwent bladder instillation and/or transurethral resection had a 30% decreased 10-year mortality risk compared with those managed with observation, the investigators reported in Cancer. After accounting for ...